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产品 | Intermediates

  产品名称    Tenofovir
  CAS#    147127-20-6; 206184-49-8; 107021-12-5
  Synonyms    (R)-PMPA; (R)-9-(2-phosphonomethoxypropyl)adenine; 1-(6-Aminopurin-9-yl)propan-2-yloxymethylphosphonic acid hydrate
  中文名    泰诺福韦; 替诺福韦;
  Molecular Formula    C9H16N5O5P

Parameter

 

Limit

Appearance

:

White or almost white powder

Identification (By HPLC)

:

The retention time of the principal peak in the chromatogram of the sample solution corresponds to that in the obtained chromatogram of the standard solution.

Solubility

:

Slightly soluble in water and practically insoluble in methanol.

Assay (HPLC, on dry basis)

:

98 - 102 %

Unspecified Impurities (HPLC)

:

NMT 1.0 %

Total Impurities (HPLC)

:

NMT 3.0 %

Water Content

:

NMT 6.0 %

Specific Rotation (on dry basis)

:

- 19.00 to - 23.00

CAS number : 147127-20-6 (anhydous); 107021-12-5 (racemic)

                                        

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